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A decrease of 0.1 pH units may not seem like much, but because the pH scale is logarithmic, each unit on the pH scale represents a tenfold change in acidity
for instance, its not known to affect how other drugs are metabolized or to block their action
Among the intestinal helminths, experimental vaccines against hookworm infections have been developed using single antigens derived from larvae [22] and administered with different adjuvants, including alum, in which there was a reduction of approximately 30% in challenge hookworm survival in animals immunized with these vaccines [23]
A product specifically formulated to include both actives in a stable, pH-balanced system with appropriate attention to chelation, emulsion type, and antioxidant systems is a meaningfully different situation from ad-hoc layering of two separate products
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